KMID : 0613820090190111568
|
|
Journal of Life Science 2009 Volume.19 No. 11 p.1568 ~ p.1574
|
|
Cardiovascular Responses over the Time Course during Muscle Group ¥² Stimulation in Prehypertensive Individuals
|
|
Park Won-Il
Nho Ho-Sung Park Si-Young Choi Hyun-Min Lee Joon-Hee Chun Jong-Mok Kim Jong-Kyung Shim Jae-Kun
|
|
Abstract
|
|
|
The purpose of this study was to investigate whether group ¥² muscle afferents play an important role eliciting abnormal blood pressure response mediated during passive muscle stretch in prehypertensive individuals. Eleven middle-aged prehypertensive men (average BP 133/80 §®Hg) and nine middle-aged normotensive men (average BP 119/74 §®Hg) participated in this study. After 1 min rest baseline data collection, the subject¡¯s foot was flexed (dorsiflexion) by an automated cybex for one minute. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP), heart rate, stroke volume, cardiac output, and total peripheral resistance were continuously measured on a beat-by-beat basis from a finger via a Finapres device for 1 minute. To evaluate the role of mechanoreflex, a component of exercise pressor reflex, SBP, DBP, and MAP responses over the course of time were examined. The results showed that the pressor response mediated by the muscle mechanoreflex was faster in prehypertensive individuals compared to the normotensive individuals. The substantial pressor response was observed within mean 20 sec of the onset of passive stretch in prehypertension, while mean 45 sec in normotension (p£¼0.05). It is concluded that excessive pressor response produced during exercise in prehypertension may be due to the dysfunction of the mechano-receptors.
|
|
KEYWORD
|
|
Prehypertension, exercise pressor response, passive muscle stretch
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|